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Isaac “Zak” Kohane is the chair of biomedical informatics at Harvard Medical School. He’s uniquely situated for the explosion of AI in health care, having a Ph.D. in computer science as well as an M.D. He’s also been a proponent of using clinical trials to test the effectiveness of AI in medicine.
Last fall, he proposed in NEJM something I thought was interesting: Testing ChatGPT’s advice not against doctor’s advice, but against the real-world alternative to asking Dr. Google or Dr. ChatGPT: Not going to the doctor at all. However, that comes with trade-offs, as we saw a couple weeks ago — not including the best possible control group means we miss out on learning where AI’s advantages are compared to other methods.
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